Top 5 Ways Intermittent Fasting Complements a Gut Healing Diet
Intermittent Fasting has become a very popular way to lose weight. Many people are choosing IF over other forms of weight loss approaches like restricting calories or eliminating macros or food groups from one’s diet.
While combining IF with nutrient-dense, gut-friendly foods supports optimal benefits, IF alone can be less restrictive and more freeing for many people seeking to reduce calorie intake without strict food exclusions. The key is focusing on overall nutrient quality during eating windows even if the fasting approach doesn’t prescribe specific food groups
IF is a flexible weight loss approach that usually involves fewer food restrictions than diets like paleo or vegan, and its benefits improve when paired with a diet rich in whole, gut-supportive foods
What is Intermittent Fasting?
The first thing that we need to consider is what Intermittent Fasting really is. This can be a bit tricky, as there are several forms of IF, and this is not always mentioned clearly in the studies that are performed.
Intermittent fasting patterns are often described as protocols. These protocols define fasting and eating windows and sometimes specify allowed calorie intake during the fast.
The most common IF protocols:
16:8 or 18:6 method (can even be 20:4, etc.): This is where you fast for 16 to 20+ hours, and eat for the remaining hours in the day. The 16:8 approach is often referred to as the ‘Leangains’ method and is one of the most commonly used IF patterns.
There is a lot of evidence for the benefits of fasting as a whole. For people pursuing a gut-supportive diet, fasting can create structured breaks from eating, which may support better awareness of hunger cues and food choices. Here are some evidence-backed benefits of intermittent fasting.
Gut Bacteria and Weight Loss
Most evidence regarding IF and weight loss shows that it works just as well as other forms of dieting 1. This makes sense, because IF primarily changes when you eat rather than prescribing specific foods, although in practice many people also adjust what and how much they eat. By limiting the hours available for eating, many people naturally reduce their total calorie intake over time, which is the main driver of weight loss with IF.
Many people believe that it is best to eat many smaller meals more frequently in the day, but this is a myth. Overall, studies do not show a meaningful difference in weight loss between very frequent eating and fewer meals per day when total calorie intake is controlled 2. For many people, eating more often can make it easier to overeat, especially if snacks are energy-dense. Fewer, more intentional meals or snacks can help some individuals better control overall intake. 3.
Intermittent fasting lowers the chance of consuming snacks. All of the food you eat is generally centered around three meals. Therefore, when you do eat, make it count!
To experience the true benefits of intermittent fasting, you often have to plan your meals out. Just to make sure that your plate is balanced with lots of plant based colorful foods, lean meats, and various gut healing foods. Otherwise, you run the risk of a nutrient deficiency.
When you restrict your diet, what you put into your gut after the fast is broken is vital. If you consume food rich in unhealthy fats and artificial ingredients, it can starve the beneficial bacteria in your gut while nourishing the pathogenic ones. If harmful intestinal flora takes over your gut, it will make losing weight more difficult.
Improved Digestive Health
The average American eats far too often throughout the day 4. Our ancestors have never had such an abundance of food, so they rarely ate all day as many Americans do. This constant digestion of food can wreak havoc on our microbiome.
Longer fasting windows have been associated in some studies with improvements in metabolic markers, which may also benefit gut health 5. This makes a lot of sense if you think about it, especially now that the Standard American Diet is so processed and full of junk.Lower Risk of Gastrointestinal Illness and Diabetes
Increased blood glucose levels, GI disorders, increased weight, and poor gut health has a complex, intertwined relationship 6. Research suggests:
” Diabetes pathogenesis could be a result of specific pathogens, but metabolites produced by gut microbiota, such as bile acids, also play an important part.”
– J Diabetes Investig.
Harmful changes in intestinal bacteria can contribute to elevated blood glucose levels and increased diabetes risk, as imbalances in the gut microbiome are associated with insulin resistance and type 2 diabetes.
It is always best to keep your blood glucose levels at a manageable level. This goal can be attained through calorie restriction, or by following a regimented, healthy gut diet plan. However, some evidence has been coming to light, shining a light on the potential of IF as a viable alternative 7.
A lot of this benefit can be simply due to consuming less added sugars in the long term. But fasting can be uniquely helpful, as it causes the body not to have the regular glucose spikes that it has after every meal. Since you are not eating for long periods of time, your body does not have a glucose spike every couple of hours or so.
Reduces Inflammation
A lot of what we eat and do increases inflammation in our body. These decisions can be deadly in the long run.
Long-term inflammation is linked with increased risk of:
- Diabetes
- Heart Disease
- High Blood Pressure
- Cancer (including digestive system cancers)
- Autoimmune Disease (e.g., rheumatoid arthritis, lupus)
- Leaky Gut Syndrome (increased intestinal permeability)
- Growth of Free Radicals
-
Microbial dysbiosis
Moderate exercise and following a diet rich foods that support gut health may reduce inflammation. Following an intermittent fasting protocol further enhances this benefit.
To date, research in humans and animals suggests that certain intermittent fasting approaches can reduce inflammatory markers in the body, although findings vary by protocol and population. Most available studies are relatively small and short term, so more long-term, well-controlled human research is needed to confirm the extent and durability of these anti-inflammatory effects 8.
Increases Cardio Health
When it comes to potentially preventable deaths in the world, heart disease tops that list. Many people in developed countries do not eat enough fresh produce, lean clean meats, or whole foods in decent quantities anymore. Instead, most of what we eat is processed and filled with junk. As a result, these foods start to clog our arteries, create a dysbiotic gut state, increase inflammation, and before long, we are suffering from heart disease.

There is currently limited evidence that intermittent fasting (IF) alone prevents heart disease more effectively than other healthy eating patterns. Research suggests, however, that following IF protocols may help reduce several risk factors associated with heart disease, such as body weight, blood pressure, blood lipids, and markers of insulin resistance. Benefits of preventive strategies like intermittent fasting may be further enhanced when they are combined with maintaining a healthy weight and following a nutrient-dense, gut-supportive eating plan. 9 10.
Intermittent Fasting and Gut Health
Many of these studies are small, but the findings so far are promising. Besides, any diet that works for you, and helps you to lower your weight in order to also lower other risk factors for disease is always a plus.
Intermittent fasting, when done correctly, is an effective approach for both losing weight and maintaining a healthy weight. Because it has few downsides, it supports your body’s overall well-being. If other diets haven’t worked for you, consider giving intermittent fasting a try—you may be surprised by how good you feel.
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Resources
- 1 Tello, Monique. “Intermittent Fasting: Surprising Update.” Harvard Health Blog, 26 June 2018, www.health.harvard.edu/blog/intermittent-fasting-surprising-update-2018062914156.
- 2 Bellisle, F, et al. “Meal Frequency and Energy Balance.” The British Journal of Nutrition, U.S. National Library of Medicine, Apr. 1997, www.ncbi.nlm.nih.gov/pubmed/9155494.
- 3 Cameron, Jameason D, et al. “Increased Meal Frequency Does Not Promote Greater Weight Loss in Subjects Who Were Prescribed an 8-Week Equi-Energetic Energy-Restricted Diet.” The British Journal of Nutrition, U.S. National Library of Medicine, Apr. 2010, www.ncbi.nlm.nih.gov/pubmed/19943985.
- 4 Koopman, Karin E., et al. “Hypercaloric Diets with Increased Meal Frequency, but Not Meal Size, Increase Intrahepatic Triglycerides: A Randomized Controlled Trial.” Hepatology, John Wiley & Sons, Ltd, 13 May 2014, aasldpubs.onlinelibrary.wiley.com/doi/full/10.1002/hep.27149.
- 5 Beli, Eleni, et al. “Restructuring of the Gut Microbiome by Intermittent Fasting Prevents Retinopathy and Prolongs Survival in Db/Db Mice.” Diabetes, American Diabetes Association, 1 Sept. 2018, diabetes.diabetesjournals.org/content/67/9/1867.
- 6 Aw, W., & Fukuda, S. (2017). Understanding the role of the gut ecosystem in diabetes mellitus. Journal of diabetes investigation, 9(1), 5–12. doi:10.1111/jdi.12673.
- 7 “Intermittent Fasting vs Daily Calorie Restriction for Type 2 Diabetes Prevention: a Review of Human Findings.” Translational Research, Mosby, 12 June 2014, www.sciencedirect.com/science/article/pii/S193152441400200X.
- 8 Lavin, Desiree N, et al. “Fasting Induces an Anti-Inflammatory Effect on the Neuroimmune System Which a High-Fat Diet Prevents.” Obesity (Silver Spring, Md.), U.S. National Library of Medicine, Aug. 2011, www.ncbi.nlm.nih.gov/pubmed/21527899.
- 9 Varady, Krista A, et al. “Short-Term Modified Alternate-Day Fasting: a Novel Dietary Strategy for Weight Loss and Cardioprotection in Obese Adults.” The American Journal of Clinical Nutrition, U.S. National Library of Medicine, Nov. 2009, www.ncbi.nlm.nih.gov/pubmed/19793855.
- 10 “Effects of Intermittent Fasting on Metabolism in Men.” Revista Da Associação Médica Brasileira, No Longer Published by Elsevier, 31 Mar. 2013, www.sciencedirect.com/science/article/pii/S0104423013000213.